replication data and code Search Results


90
Epigenomics ag replication timing and epigenomic data
a Quantile-quantile plot of fishHook p -values to assess significance of gene mutational burden after removing confounders. The p -values were obtained by comparing observed mutational rate to the right tail (one-sided) of the expected mutational rates derived from a gamma-Poisson model of genome-wide mutational density and the covariates replication timing, <t>epigenetic</t> state, and sequence context. In the first stage of CIRCLE, six significant genes were identified below a false-discovery threshold (FDR < 0.1). b Odds ratios (ORs) of response to ICB therapy in patients with a high or moderate impact mutation in the indicated gene as compared to patients that do not have a high or moderate mutation in the given gene ( n = 272 patients). Error bars indicate the 95% confidence interval of the odds ratio. ORs greater than one indicate enrichment in responders and ORs less than one indicate enrichment in non-responders. Statistical significance was tested using a two-sided Wald’s test of coefficients with multiple-hypothesis correction (FDR < 0.2).
Replication Timing And Epigenomic Data, supplied by Epigenomics ag, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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replication timing and epigenomic data - by Bioz Stars, 2026-07
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GeneCentric Diagnostics discovery scan and replication data
a Quantile-quantile plot of fishHook p -values to assess significance of gene mutational burden after removing confounders. The p -values were obtained by comparing observed mutational rate to the right tail (one-sided) of the expected mutational rates derived from a gamma-Poisson model of genome-wide mutational density and the covariates replication timing, <t>epigenetic</t> state, and sequence context. In the first stage of CIRCLE, six significant genes were identified below a false-discovery threshold (FDR < 0.1). b Odds ratios (ORs) of response to ICB therapy in patients with a high or moderate impact mutation in the indicated gene as compared to patients that do not have a high or moderate mutation in the given gene ( n = 272 patients). Error bars indicate the 95% confidence interval of the odds ratio. ORs greater than one indicate enrichment in responders and ORs less than one indicate enrichment in non-responders. Statistical significance was tested using a two-sided Wald’s test of coefficients with multiple-hypothesis correction (FDR < 0.2).
Discovery Scan And Replication Data, supplied by GeneCentric Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/replication+data+and+code/pmc01785338-220-3-6?v=GeneCentric+Diagnostics
Average 90 stars, based on 1 article reviews
discovery scan and replication data - by Bioz Stars, 2026-07
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Broad Institute Inc aj crohn’s disease and control exome replication data set [ajex]
a Quantile-quantile plot of fishHook p -values to assess significance of gene mutational burden after removing confounders. The p -values were obtained by comparing observed mutational rate to the right tail (one-sided) of the expected mutational rates derived from a gamma-Poisson model of genome-wide mutational density and the covariates replication timing, <t>epigenetic</t> state, and sequence context. In the first stage of CIRCLE, six significant genes were identified below a false-discovery threshold (FDR < 0.1). b Odds ratios (ORs) of response to ICB therapy in patients with a high or moderate impact mutation in the indicated gene as compared to patients that do not have a high or moderate mutation in the given gene ( n = 272 patients). Error bars indicate the 95% confidence interval of the odds ratio. ORs greater than one indicate enrichment in responders and ORs less than one indicate enrichment in non-responders. Statistical significance was tested using a two-sided Wald’s test of coefficients with multiple-hypothesis correction (FDR < 0.2).
Aj Crohn’s Disease And Control Exome Replication Data Set [Ajex], supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/replication+data+and+code/pmc05643259-74-25-28?v=Broad+Institute+Inc
Average 90 stars, based on 1 article reviews
aj crohn’s disease and control exome replication data set [ajex] - by Bioz Stars, 2026-07
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EMC Inc system and method for managing replication of data in a data storage environment
a Quantile-quantile plot of fishHook p -values to assess significance of gene mutational burden after removing confounders. The p -values were obtained by comparing observed mutational rate to the right tail (one-sided) of the expected mutational rates derived from a gamma-Poisson model of genome-wide mutational density and the covariates replication timing, <t>epigenetic</t> state, and sequence context. In the first stage of CIRCLE, six significant genes were identified below a false-discovery threshold (FDR < 0.1). b Odds ratios (ORs) of response to ICB therapy in patients with a high or moderate impact mutation in the indicated gene as compared to patients that do not have a high or moderate mutation in the given gene ( n = 272 patients). Error bars indicate the 95% confidence interval of the odds ratio. ORs greater than one indicate enrichment in responders and ORs less than one indicate enrichment in non-responders. Statistical significance was tested using a two-sided Wald’s test of coefficients with multiple-hypothesis correction (FDR < 0.2).
System And Method For Managing Replication Of Data In A Data Storage Environment, supplied by EMC Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/replication+data+and+code/us07546428-1-22-29?v=EMC+Inc
Average 90 stars, based on 1 article reviews
system and method for managing replication of data in a data storage environment - by Bioz Stars, 2026-07
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KU Leuven replication data for: the portrait of elisabeth braderic – scientific reports and imaging
a Quantile-quantile plot of fishHook p -values to assess significance of gene mutational burden after removing confounders. The p -values were obtained by comparing observed mutational rate to the right tail (one-sided) of the expected mutational rates derived from a gamma-Poisson model of genome-wide mutational density and the covariates replication timing, <t>epigenetic</t> state, and sequence context. In the first stage of CIRCLE, six significant genes were identified below a false-discovery threshold (FDR < 0.1). b Odds ratios (ORs) of response to ICB therapy in patients with a high or moderate impact mutation in the indicated gene as compared to patients that do not have a high or moderate mutation in the given gene ( n = 272 patients). Error bars indicate the 95% confidence interval of the odds ratio. ORs greater than one indicate enrichment in responders and ORs less than one indicate enrichment in non-responders. Statistical significance was tested using a two-sided Wald’s test of coefficients with multiple-hypothesis correction (FDR < 0.2).
Replication Data For: The Portrait Of Elisabeth Braderic – Scientific Reports And Imaging, supplied by KU Leuven, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/replication+data+and+code/10__1080_slash_00393630__2024__2429340-302-2-16?v=KU+Leuven
Average 90 stars, based on 1 article reviews
replication data for: the portrait of elisabeth braderic – scientific reports and imaging - by Bioz Stars, 2026-07
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Drott Medizintechnik GmbH replication data and code
a Quantile-quantile plot of fishHook p -values to assess significance of gene mutational burden after removing confounders. The p -values were obtained by comparing observed mutational rate to the right tail (one-sided) of the expected mutational rates derived from a gamma-Poisson model of genome-wide mutational density and the covariates replication timing, <t>epigenetic</t> state, and sequence context. In the first stage of CIRCLE, six significant genes were identified below a false-discovery threshold (FDR < 0.1). b Odds ratios (ORs) of response to ICB therapy in patients with a high or moderate impact mutation in the indicated gene as compared to patients that do not have a high or moderate mutation in the given gene ( n = 272 patients). Error bars indicate the 95% confidence interval of the odds ratio. ORs greater than one indicate enrichment in responders and ORs less than one indicate enrichment in non-responders. Statistical significance was tested using a two-sided Wald’s test of coefficients with multiple-hypothesis correction (FDR < 0.2).
Replication Data And Code, supplied by Drott Medizintechnik GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/replication+data+and+code/10__1080_slash_13698249__2018__1525677-165-25-20?v=Drott+Medizintechnik+GmbH
Average 90 stars, based on 1 article reviews
replication data and code - by Bioz Stars, 2026-07
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Image Search Results


a Quantile-quantile plot of fishHook p -values to assess significance of gene mutational burden after removing confounders. The p -values were obtained by comparing observed mutational rate to the right tail (one-sided) of the expected mutational rates derived from a gamma-Poisson model of genome-wide mutational density and the covariates replication timing, epigenetic state, and sequence context. In the first stage of CIRCLE, six significant genes were identified below a false-discovery threshold (FDR < 0.1). b Odds ratios (ORs) of response to ICB therapy in patients with a high or moderate impact mutation in the indicated gene as compared to patients that do not have a high or moderate mutation in the given gene ( n = 272 patients). Error bars indicate the 95% confidence interval of the odds ratio. ORs greater than one indicate enrichment in responders and ORs less than one indicate enrichment in non-responders. Statistical significance was tested using a two-sided Wald’s test of coefficients with multiple-hypothesis correction (FDR < 0.2).

Journal: Nature Communications

Article Title: Recurrent somatic mutations as predictors of immunotherapy response

doi: 10.1038/s41467-022-31055-3

Figure Lengend Snippet: a Quantile-quantile plot of fishHook p -values to assess significance of gene mutational burden after removing confounders. The p -values were obtained by comparing observed mutational rate to the right tail (one-sided) of the expected mutational rates derived from a gamma-Poisson model of genome-wide mutational density and the covariates replication timing, epigenetic state, and sequence context. In the first stage of CIRCLE, six significant genes were identified below a false-discovery threshold (FDR < 0.1). b Odds ratios (ORs) of response to ICB therapy in patients with a high or moderate impact mutation in the indicated gene as compared to patients that do not have a high or moderate mutation in the given gene ( n = 272 patients). Error bars indicate the 95% confidence interval of the odds ratio. ORs greater than one indicate enrichment in responders and ORs less than one indicate enrichment in non-responders. Statistical significance was tested using a two-sided Wald’s test of coefficients with multiple-hypothesis correction (FDR < 0.2).

Article Snippet: Replication timing and epigenomic data were obtained from the ENCODE and Roadmap Epigenomics ( Supplementary Data ) projects, respectively , .

Techniques: Derivative Assay, Genome Wide, Sequencing, Mutagenesis